Hydranencephaly after Maternal Butane-gas Intoxication during Pregnancy . Hydranence’phalie apr.?s intoxication maternelle par le gaz butane durant la. Autoerotic Accident by Inhalation of Propane-Butane Gas Mixture Toxicologic investigations revealed an intoxication with propane and butane .. kan ve doku örneklerinde gaz komponentlerinin analizinin yap›labilmesi tan›. Butane is a colourless and flammable gas with a gasoline-like or natural gas This paper discusses the medico-legal approach for this type of intoxication.

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A total uncertainty factor of 3 is considered sufficient for toxicokinetic and toxicodynamic differences between individuals and interspecies differences for the following reasons. Butane abuse associated encephalopathy; pp. The btuane had undergone an operation for a cardiac ventricular septal defect at the age of Int J Clin Prac ; Concentrations of hydrocarbons in tissues as a measure of toxicity; pp.

Ultrasonography and neuroradiological studies CT scan and angiography showed an almost complete absence of both cerebral hemispheres. Inhalation for 2 h, butane concentrations not specified. Isobutane is primarily used by refineries to enhance increase the octane number of motor gasoline.

Thus, the AEGL-2 values for min and 1, 4, intoxicaion 8 h will be set equal to the 2-h concentration.

Suicide by Inhalation of Suffocative Gas

Downloads Download data is not yet available. Monkeys No data were available. She had poor head-control. HN 3 NH radical. Le thalamus, le tronc c6rkbral et le cervelet Ctaient indemnes. An ultrasound at week 39 of the pregnancy showed an almost complete absence of brain tissue in the fetus. There are several reports of Fig.

Asphyxia due to oxygen deficiency by gaseous substances. However, a large uncertainty factor is not necessary considering the steep concentration-response curve; a large factor also would lead to unrealistically low AEGL-2 values that butxne be similar to the AEGL-1 values. Most of these cases involved inhalant abusers with repetitive exposure to butane. Exposure groups consisted of laboratory or clerical personnel males and females, years of age.


The concentrations were analyzed periodically and adjustments made to maintain the predetermined concentrations. The portion of left occipital inyoxication has been spared umer limbs were hvootonic. Die Autoren sind der Ansicht, daR die MiRbildung durch eine intrauterine Anoxie hervorgerufen wurde, die wahrend der fetalen Hirnentwicklung aufgetreten ist.

These were probably rather minor effects. Diese Befunde entsprechen einer Hydranencephalie. A species with a relatively high susceptibility is used as starting point. Fetal sonogram at 39 weeks of gestation axial view of fetal skull.

The results of microbial mutation test for forty-three industrial chemicals; pp. European Commission, European Chemicals Bureau [online]. The duration and concentration of butane exposure were not reported, nor was the amount of time that elapsed before resuscitation commenced.

Inhalation of butane can cause euphoriadrowsinessunconsciousnessasphyxiacardiac arrhythmiafluctuations in blood pressure and temporary memory loss, when abused directly from a highly pressurized container, and can result in death from asphyxiation and ventricular fibrillation.

Butane is also used as lighter fuel for a common lighter or butane torch and is sold bottled as a fuel for cooking, barbecues and camping stoves. Butanes are highly flammable, colorless, easily liquefied gases that quickly vaporize at room temperature. Butane appears to be negative in the Ames test, with and without metabolic activation citation of an unpublished report in Moore Hence, the rationale described in Section 6.

Posterior- carotid artery are hypertrophied double arrowfossa structures are usually normal. The Bulletin of Legal Medicine is an open access scientific journal. Case reports indicate that single exposure to high concentrations of butane might cause severe brain damage in the fetus, but no adequate human or animal data are available for a quantitative evaluation of this end point.


Standards and guidelines for short-term exposures to butane are presented in Table Myocardial infarction and neurodevastation following butane inhalation; p. The only study with human volunteers Patty and Yant is rather old and focused on the warning properties of butane. Most commercially available butane also contains a certain amount of contaminant oil which can be removed through filtration but which will otherwise leave a deposit at the point of ignition and may eventually block the uniform flow of gas.

Committee on Updating of Occupational Exposure Limits. Shugaev exposed rats sex and strain not specified to varying concentrations of butane for 4 h.

Butane – Drug and Alcohol Information and Support in Ireland –

Butane at a concentration of 10, ppm min exposure can be regarded as ingoxication boundary for the drowsiness reported; although some drowsiness may be noticed, it will not be experienced as discomfort.

However, the LC 01 can be calculated because the mean is known and the standard deviation of the underlying lognormal distribution can be derived from these data.

Alcohol diary Alcohol use Balance Sheet Change Plan worksheet Goal Setting Guidelines for supporters How to stick to your plans Tips for drinking less What to do about boredom Young people and drink Why young people drink What are the gzz and effects? Surviving mice recovered within a few min after exposure ended. The 2-h LC 01 for mice wasppm and the 4-h LC 01 for rats wasppm. Thirteen intixication these cases were associated with butane Bowen et al.