KAPVAY PACKAGE INSERT PDF

Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Kapvay (clonidine). Concordia Pharmaceuticals Inc.: KAPVAY (clonidine hydrochloride) extended- release is indicated for the treatment of attention deficit. The following text is taken verbatim from the Kapvay package insert: “The dose of Kapvay [ER clonidine], administered either as monotherapy or as adjunctive.

Author: Kigagore Voodoogami
Country: Timor Leste
Language: English (Spanish)
Genre: Medical
Published (Last): 3 May 2006
Pages: 291
PDF File Size: 15.24 Mb
ePub File Size: 14.76 Mb
ISBN: 151-7-42891-932-7
Downloads: 67463
Price: Free* [*Free Regsitration Required]
Uploader: Mular

Clonidine is also used and as an aid in smoking cessation therapy and to diagnose pheochromocytoma a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heart rate.

Patients were randomly assigned to one of two treatment groups: What special precautions should I follow? It may harm them. Especially tell your doctor if you take: Your doctor will probably decrease apckage dose gradually over ineert to days for the regular tablet and 3 to 7 days for the extended-release tablet.

Titrate KAPVAY slowly and monitor vital signs frequently in patients with cardiac conduction abnormalities or patients concomitantly treated with other sympatholytic drugs.

PDR Search

Other uses for this medicine What special precautions should Pavkage follow? The cumulative proportion of patients with treatment failure over time during the double-blind phase is displayed in Figure 2. KAPVAY clonidine hydrochloride extended-release is a centrally acting alpha 2 -adrenergic agonist available as 0.

Your doctor may prescribe a low-salt or low-sodium diet.

For more information, ask your doctor or pharmacist. Older adults should not usually use clonidine because it is not as safe as other medications that can be used to treat the same condition.

These doses are approximately 3 times the MRHD of 0. Other uses for this medicine. Patients should be instructed not to discontinue KAPVAY therapy without consulting their physician due to the potential risk of withdrawal effects. The half-life increases up to 41 hours in patients with severe impairment of renal function.

  ASME BPE 2009 PDF

Plasma clonidine concentrations in children and adolescents 0. Advise patients that KAPVAY must be swallowed whole, never crushed, cut, or chewed, and may be taken with or without food. Avoid becoming dehydrated or overheated. Effect on Blood Pressure and Heart Rate Kkapvay patients that completed 5 weeks of treatment in a controlled, fixed-dose monotherapy study in pediatric patients, during the treatment period the maximum placebo-subtracted mean change in systolic blood pressure was Padkage were randomly assigned to one of the following three treatment groups: The maximum placebo-subtracted mean change in heart rate was In cases of poisoning or suspected over dosage, the drug’s identity should be verified by chemical analysis.

Ask your pharmacist for a list of the ingredients. Just take the next dose at your regular time.

Clonidine: MedlinePlus Drug Information

Since only a minimal amount of clonidine is removed during routine hemodialysis, there is no need to give supplemental KAPVAY following dialysis. May worsen sinus node dysfunction and atrioventricular AV block, especially in patients taking other sympatholytic drugs. By stimulating alpha 2 -adrenergic receptors in the brain stem, clonidine reduces sympathetic outflow from the central nervous system and decreases peripheral resistance, renal vascular resistance, heart rate, and blood pressure.

Although studies of the effect of renal kapay and studies of clonidine excretion have not been performed with KAPVAY, results are likely to be similar to those of the immediate release formulation. Clonidine may help to control your condition but will not cure it. Clonidine stimulates alpha 2 -adrenergic receptors in the brain.

Advise patients to avoid use with alcohol. However, you should not flush this medication down the toilet. What should I do if I forget a dose? The frequency of CNS depression may be higher in children than adults. Ask your doctor or pharmacist for a list of these medicines, if you are not sure if your medicine is listed above. The dose of KAPVAY, administered either as monotherapy or as adjunctive therapy to a psychostimulant, should be individualized according to the therapeutic needs and response of the patient.

  AZBOX PREMIUM PLUS MANUAL PDF

No embryotoxic or teratogenic effects were seen in rabbits administered oral clonidine hydrochloride during organogenesis at doses up to 3 times the MRHD. Consider the potential for additive sedative effects with CNS depressant drugs. Treatments were separated by one-week washout periods. Reactions have included generalized rash, urticaria, and angioedema [see Adverse Reactions 6 ].

Monitor patients carefully for hypotension and bradycardia, and titrate to higher doses cautiously. A total of 73 patients experienced treatment failure in the double-blind phase: Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Your doctor should check your heart rate and blood pressure before starting treatment and regularly during treatment with KAPVAY. Clonidine is not a central nervous system stimulant.

Kapvay | FULL Prescribing Information |

Advise patients to avoid becoming dehydrated or overheated. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Instead, the best way to dispose of your medication is through a medicine take-back program. Drugs that affect sinus node function or AV node conduction e.

Avoid concomitant use of drugs with additive effects unless clinically indicated. The impact of renal impairment on the pharmacokinetics of clonidine in children has not been assessed. Measure heart rate and blood pressure prior to initiation of therapy, following dose increases, and periodically while on therapy.